Ketamine Versus Etomidate for Rapid Sequence Intubation

• Status: Completed
• Trial end date: 2015-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hennepin Healthcare Research Institute; Minneapolis Medical Research Foundation
• Treatments: Etomidate; Ketamine

Criteria

Inclusion Criteria:

• 18 years of age

• Undergoing rapid sequence intubation (RSI) in the Emergency Department

Exclusion Criteria:

• Known contraindication to ketamine or etomidate

• Patient has a condition in which an increase in heart rate or blood pressure would be hazardous, as judged by the treating physician

• Patient is known or suspected of having increased intracranial pressure, based on the history and physical examination performed by the treating physician.

• Females of child-bearing age, defined as 18-50 years, who do not have a documented pregnancy test in this institution confirming that they are not pregnant or who do not have a confirmed surgical procedure preventing pregnancy, i.e., tubal ligation, hysterectomy. The timing of the pregnancy test at which the investigative team will consider a subject to be non-pregnant is a documented negative test during current hospitalization or upon direct transfer from outside institution during current illness.

• Patient declines participation in the trial by wearing a bracelet marked "KvE declined"

• Prisoner