Ketamine Versus Lidocaine Nebulization for Awake Fiberoptic Intubation

• Status: Completed
• Trial end date: 2019-07-25
• Target enrollment: 0
• Participant gender: All

Summary

This randomized double-blinded study is performed to compare ketamine versus lidocaine for nebulization for awake nasal fiberoptic intubation as regard efficacy and side effects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Ketamine; Lidocaine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical status I and II of both sexes with body weight from 60-90 kg, and planned for elective awake nasal fiberoptic intubation due to expected difficulty in airway management (e.g. limited mouth opening, trismus, mandibular/ maxillary swellings or tumors, ludwig's angina, or other indications).

Exclusion Criteria:

• body weight < 60 kg or > 90 kg

• uncooperative, with mental or psychological problems

• known allergy to any of the study drugs

• pregnancy

• hypertension

• cardiac disease

• liver or renal impairment

• epilepsy,

• asthmatic,

• previous bad experience of awake intubation,

• emergency operations or

• coagulation abnormalities