Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.
Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The introduction of the laparoscopic technique for cholecystectomy significantly reduced the
incidence and intensity of postoperative pain, with improvement in other markers, such as
patient satisfaction, and reduction in hospital stay. However, pain in the postoperative
period of laparoscopic cholecystectomy is still a concern that challenges modern
anesthesiology. Ketamine and magnesium sulfate are two blockers of N-methyl-D-aspartate
(NMDA) receptors with the ability to reduce postoperative pain and postoperative opioid
consumption. A frequent concern among anesthesiologists is the quality and time of awakening
in patients receiving these medications The main objective of this trial is to compare the
quality and time of awakening in patients receiving magnesium sulfate or ketamine.
The secondary objective is to compare postoperative analgesia during the postoperative
hospital stay.
Hypothesis: Our hypothesis is that patients have a faster awakening when they receive
magnesium sulfate as an analgesic adjunct, when compared to patients who receive ketamine .
Design: this is a prospective, controlled, covered and randomly distributed trial.