Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain

• Status: Unknown status
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Postoperative pain after thoracic surgery is associated with adverse outcomes. The current strategy to prevent postoperative pain is the use of regional anesthesia and analgesic agents. In video-assisted thoracic surgery (VATS), thoracic paravertebral block has become the standard analgesic regimen which results in decreased postoperative pain and opioid consumption.

The investigator would like to study the analgesic efficacy of low dose intravenous ketamine infusion during surgery in combination with thoracic paravertebral block on postoperative pain after VATS in a randomized study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologist physical status 1-3

• Scheduled for elective video-assisted thoracic surgery

• Able to operate a patient-controlled analgesia device (PCA)

Exclusion Criteria:

• History of morphine allergy

• History of bupivacaine allergy

• Contraindication for ketamine infusion

• Contraindication for thoracic paravertebral block

• Anticipated postoperative positive pressure ventilation

• Body mass index more than 35

• Any known psychiatric disorder