Ketamine and Changes of the Short Portable Mental Status Questionnaire

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: All

Summary

• Cognitive changes are related to aging, affecting the performance of older patients in the solution of problems and the execution of tasks.

This phenomenon has been observed as a decline of neurophysiological domains, especially memory, and the velocity of thought.

• Anesthesia and surgery performed contributes to its development then, is named post-operative cognitive dysfunction (POCD). The incidence varies due to conditions of:

1. Anesthesia and surgery.

2. The time elapsed after surgery.

3. The population studied, and the type of cognitive test employed.

• The aim of this study is to evaluate the changes around the Short Portable Mental Status Questionnaire (SPMSQ-E) after ketamine administration on ophthalmic surgery on the common conditions of geriatric patients, -comorbid and settings as minor surgery-.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Instituto Mexicano del Seguro Social
• Collaborator: National Polytechnic Institute, Mexico
• Treatments: Ketamine; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Patients be over 60 years and older.

• Intraocular pressure less than 20 millimeter of mercury.

• American Society of Anaesthesiologists (ASA) physical status classification, I-III.

Exclusion Criteria:

• History of psychosis or schizophrenia.

• Nephropathy.

• Difficult to control hypertension.

• Uncontrolled hepatic disorders.

• Allergy to ketamine.

• Moderate to severe depression.

• Post-operative delirium.

• Needed to use medications other than those contemplated in the study.