Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal
Status:
Withdrawn
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
This study is designed to evaluate the addition of ketamine to dexmedetomidine as adjunctive
therapies of severe alcohol withdrawal in medical ICU patients. Specifically, this study will
assess whether the combination of ketamine and dexmedetomidine reduces the doses of
conventional agents used for alcohol withdrawal while maintaining patient comfort and safety
and will explore if the combination alters the expression of catecholamines in the serum over
time.