Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial

• Status: Active, not recruiting
• Trial end date: 2020-02-29
• Target enrollment: 0
• Participant gender: Female

Summary

Labor induction is a common pregnancy procedure worldwide. Both mechanical and pharmacologic agents are used for induction of labor. These agents reduce the incidence of cesarean delivery in women undergoing induction.

Opposite to old studies of cervical ripening, some recent studies have shown promise in reducing labor time and risk of cesarean delivery with combination methods. The effectiveness of this procedure is of major clinical importance and has a large impact in our quotidian practice.

The objective is to compare the effectiveness of a combined new method to current guidelines of our department

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Centro Hospitalar De São João, E.P.E.
• Treatments: Dinoprostone; Misoprostol

Criteria

Inclusion Criteria:

• full-term (≥ 37 weeks of gestation)

• singleton

• vertex-presenting gestations

• with no contraindication to vaginal delivery

• intact membranes

• Bishop score < 7 and cervical dilation ≤2 cm

Exclusion Criteria:

• contraindication for misoprostol

• history of previous caesarean

• rupture of membranes,

• fetal or maternal morbidities (fetal major abnormalities, FIGO definition of pathological CTG, HELLP syndrome, preeclampsia or hypertension with severe features, fetal growth restriction)