Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
This phase I/II trial is studying the side effects of giving laboratory-treated T cells and
ipilimumab together to see how well they work in treating patients with metastatic melanoma.
Treating a patient's T cells in the laboratory may help the T cells kill more tumor cells
when they are put back in the body. Monoclonal antibodies, such as ipilimumab, can block
tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
Others find tumor cells and help kill them or carry tumor-killing substances to them. Giving
laboratory-treated T cells together with ipilimumab may kill more tumor cells