Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled Trial
Status:
Completed
Trial end date:
2017-05-01
Target enrollment:
Participant gender:
Summary
Photodynamic therapy (PDT) is a well established treatment option for superficial non
melanoma skin cancer, such as superficial basal cell carcinoma (sBCC) and Bowen Disease (BD).
However, a limited uptake of the topically applied photosensitizer methyl aminolevulinate
(MAL) may reduce its efficacy. Pretreatment with an ablative carbon dioxide (CO2) laser has
recently been studied in order to enhance the skin penetration of this photosensitizer. This
study compares the results of a full ablative and a fractional ablative CO2 laser mode as
pretreatment of PDT in the management of sBCC and BD. The endpoints efficacy, pain,
aesthetics and patient preference are investigated during twelve months of follow up.
Phase:
N/A
Details
Lead Sponsor:
University Hospital, Ghent
Treatments:
Anesthetics Anesthetics, Local Epinephrine Epinephryl borate Lidocaine Methyl 5-aminolevulinate Racepinephrine