Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep
Status:
Not yet recruiting
Trial end date:
2025-08-06
Target enrollment:
Participant gender:
Summary
The purpose of this study to evaluate the effects of naltrexone plus lemborexant augmentation
compared to naltrexone plus placebo on cue-induced and non-cued alcohol cravings in people
with alcohol use disorder and insomnia. Our secondary goals are to evaluate the effects of
lemborexant plus naltrexone combination on sleep quality using self-report questionnaires and
actigraph data, depression, anxiety, and suicidal ideation.