Overview

Lemborexant Shift Work Treatment Study

Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
Insomnia and daytime sleepiness are common complaints among night shift workers, but effective sleep treatments in shift workers are lacking. The aim of this Phase IV double-blind, placebo-controlled, randomized study is to test whether a dual orexin antagonist, Lemborexant (5mg or 10mg), which would be expected to block the clock-driven orexin-mediated wakefulness during the day, will increase daytime sleep time in shift workers who complain of difficulty sleeping during the daytime compared to placebo.
Phase:
Phase 4
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Lemborexant