Letrozole /GnRH Antagonist Protocol in Women Over 40 Years Undergoing ICSI Cycle

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study To compare the clinical and laboratory outcomes of two ovarian stimulation protocols (standard GnRH antagonist protocol and aromatase inhibitor/ antagonist protocol) in women (40-44) years undergoing ICSI cycle.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University
• Treatments: Letrozole

Criteria

Inclusion Criteria:

• Women between 40- 44-years undergoing ICSI cycle with FSH less than 15 and AMH more than 0.30.

Exclusion Criteria:

• Azoospermia in male partner,

• Previous ovarian surgery,

• Severe endometriosis,

• Uterine cavity lesion

• Metabolic or endocrine disorders including hyperprolactinemia and ypo/hyperthyroidism.

• Previous failed ICSI cycle.

• BMI more than 30.