Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion

• Status: Not yet recruiting
• Trial end date: 2021-05-08
• Target enrollment: 0
• Participant gender: Female

Summary

this study will compare the efficacy of using letrozole pre treatment before misoprostol versus using misoprostol only in the induction of first trimester missed abortion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Shereen Rady Abou El-fetouh
• Treatments: Letrozole; Misoprostol

Criteria

Inclusion Criteria:

1. Maternal age more than 18 years old.

2. Gestational age less than 13 weeks confirmed by ultrasound scan on day 1 of the study.

3. Hemoglobin >10 g/dl

4. Missed abortion

Exclusion Criteria:

1. Mullerian Uterine anomalies as septate, bicornuate uterus.

2. Fibroid uterus.

3. Coagulopathy.

4. Medical disorder that contraindicate induction of abortion.

5. Allergy to misoprostol or letrozole.

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