Letrozole and Celecoxib in Treating Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Status:
Terminated
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using
letrozole may fight breast cancer by lowering the amount of estrogen the body makes.
Celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell
growth and by blocking blood flow to the tumor. Giving letrozole with celecoxib may kill more
tumor cells.
PURPOSE: This phase II trial is studying how well letrozole and celecoxib work in treating
postmenopausal women with locally advanced or metastatic breast cancer.
Phase:
Phase 2
Details
Lead Sponsor:
University of Medicine and Dentistry of New Jersey