Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and
hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long
implications, with increased risk for infertility, metabolic syndrome, and type 2 diabetes
mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary
syndrome is diagnosed in adolescents with otherwise unexplained, persistent hyperandrogenic
anovulatory symptoms that are inappropriate for age and stage of adolescence. It should be
considered in any adolescent girl with a chief complaint of hirsutism, treatment-resistant
acne, menstrual irregularity, acanthosis nigricans, and/or obesity