Lidocaine Combined Dexmedetomidine for Obturator Nerve Block

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Hypothesis: Dexmedetomidine as an adjuvant of lidocaine can decrease the median effective concentration(EC50) of lidocaine for obturator nerve block during transurethral resection of bladder tumor

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guolin Wang
• Collaborator: Tianjin Medical University General Hospital
• Treatments: Dexmedetomidine; Lidocaine

Criteria

Inclusion Criteria:

1. Subjects scheduled to undergo elective operation of TURBT on lateral wall for whom ONB was needed diagnosed through cystoscopy or CT examination preoperatively.

2. Subject's American Society of Anesthesiologists physical status is I-II.

3. The subject's parent/legally authorized guardian has given written informed consent to participate.

Exclusion Criteria:

1. Subject has a diagnosis of abnormal coagulation function.

2. Subject has a diagnosis of Diabetes mellitus.

3. Subject has a preexisting neurologic deficits of the lower extremities.

4. Subject has a history of alcohol or drug abuse.

5. Subject is pregnant or breast-feeding.

6. Subject is obese (body mass index >30kg/m2).