Lidocaine Infusion With ANI Monitoring in Spine Surgery.

• Status: Not yet recruiting
• Trial end date: 2023-03-31
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the analgesic effect of intraoperative continuous lidocaine infusion (1.5 mg/kg/h (ideal body weight)) in combination of analgesia nociception index and depth of anesthesia monitors guided anesthetics adjustment on enhanced recovery after surgery (ERAS) in patients undergoing elective lumbar spine surgery (≥2 sessions).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

1. Twenty to eighty-year-old

2. ASA class I-III patients undergoing

3. Elective lumbar spine surgery under general anesthesia

Exclusion Criteria:

1. Unable to understand the Numerical Rating Scale (NRS)

2. Severe mental disorder

3. Poor liver function

4. Pregnant or lactating women

5. Morbidly obese

6. History of epilepsy or allergy to any of the drugs used in this study

7. Current use of opioids

8. Baseline heart rate <50 beats/min

9. Arrhythmia history with cardiac rhythm device

10. Body weight <40 kg and >80kg