Lidocaine and Closed-Loop Anesthesia System

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective is to evaluate the sparing effect of Lidocaine on doses of propofol and remifentanil.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hopital Foch
• Treatments: Anesthetics; Lidocaine

Criteria

Inclusion Criteria:

• patients ASA 1, 2 or 3 scheduled for a general anesthesia surgical procedure (abdominal surgery, urology, ENT major procedure) lasting between 1 and 3 hours

Exclusion Criteria:

• age under 18 years

• simultaneous general and loco-regional anesthesia

• allergy to NSAID

• treatment with verapamil, ketamine or gabapentin

• patients receiving an opioid preoperatively

• severe hepatic insufficiency

• contra-indication to lidocaine

• contra-indication to propofol or to remifentanil

• history of central nervous system disease

• patients receiving a psychotropic treatment

• patients with a pace-maker