Liothyronine and Heart Failure. The Long Term Effect of Liothyronine on Left Ventricular Ejection Fraction (LVEF)

• Status: Completed
• Trial end date: 2014-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Purpose: The purpose of the study is to examine if treatment with liothyronine increases left ventricular ejection fraction (LVEF) in patients with stable, chronic heart failure.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jens Faber

Criteria

Inclusion Criteria:

• Patients with stable, chronic systolic heart failure

• T3 ≤1.4 nmol/l in two blood samples, TSH is to be normal

• LVEF ≤ 45 % on prior echocardiography

Exclusion Criteria:

• Established thyroid illness

• Atrial fibrillation/flutter

• More than 20% ventricular extrasystoles

• Severe chronic obstructive lung disorder

• Pregnancy. Pregnancy testing will be done for fertile women

• Age < 18 years