Lipid Biomarker Study in Men With Dyslipidemia After Simvastatin Treatment (Study MK-0000-140)(COMPLETED)

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study was to provide human lipidomics standards with simvastatin treatment that were to be used for comparison with similar preclinical studies.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• Participant is a Caucasian (including Hispanic) male

• Participant has a maximum waist size of 40 inches

• Participant does not currently use any lipid-altering medications

• Participant is in good health other than the diagnosis of dyslipidemia

Exclusion Criteria:

• Participant has had stomach ulcers within the last 3 months

• Participant has had a heart attack in the last 6 months or has angina

• Participant has chronic heart failure

• Participant has a history of stroke, seizures, or major neurological disorder

• Participant has a history of cancer

• Participant has a gastrointestinal condition that affects bowel movements

• Participant has type 1 or 2 diabetes