Lipid Emulsion in Cardiac Valve Replacement Surgery
Status:
Not yet recruiting
Trial end date:
2023-10-01
Target enrollment:
Participant gender:
Summary
Myocardial protection has become an essential adjunctive measure in cardiac surgery to bail
the myocardium out of ischemia/reperfusion-induced damage during the operation.
Experimental studies have shown that lipid emulsion infusion just before reperfusion (i.e.,
intralipid postconditioning (ILPC)) could reduce myocardial infarct sizes, improve cardiac
function, and reduce myocardial I/R injuries, despite the interesting experimental findings,
the potential clinical usage of lipid emulsion in preventing myocardial I/R injury needs to
be further investigated.