Lipid Infusion Following Major Surgery

• Status: Withdrawn
• Trial end date: 2017-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Surgery puts a lot of stress on the body, and during recovery from surgery, the body uses a lot of energy to help with healing and getting stronger. Often, sugars are given before surgery to help give the body an energy boost. Lipid solutions can also be used as an energy source and are commonly used as supplements in patients needing long-term nutrition from an intravenous route (e.g., total parenteral nutrition) when they can not eat by mouth for a medical reason. Intralipid, a solution of lipid molecules from soybeans and eggs, is commonly used for patients who need nutrition and energy supplements. The investigators wish to test whether giving Intralipid immediately after surgery can improve recovery from major surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alberta
• Treatments: Soybean oil, phospholipid emulsion

Criteria

Inclusion Criteria:

• Adult patients (>18 years old)

• Scheduled for abdominal surgery

• Provide written, informed consent

Exclusion Criteria:

• Patient refusal

• Pre-existing neurological deficit

• Existing or potential for coagulation abnormality

• Local or systemic infection

• Allergy to local anesthetic

• Contraindication to propofol

• Liver disease/compromised liver metabolism