Pain management after total knee arthroplasty is essential for optimized clinical outcomes
and higher satisfaction. Exparel (Pacira Pharmaceuticals, Parsippany, New Jersey, USA) is a
long-acting Bupivacaine extended release liposome compound that is injected peri-articularly
or as regional block. The purpose of this study was to compare the analgesic efficacy of
single administration of Exparel for local peri-articular infiltration versus adductor canal
regional block.