Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis
Status:
Completed
Trial end date:
2017-02-01
Target enrollment:
Participant gender:
Summary
Alendronate (ALN), commonly use bisphosphonates is proposed to have osteostimulative
properties in vivo and in vitro, as shown by an increase in the matrix formation, and acts as
a potent inhibitor of bone resorption. AV widely known for its wound healing, analgesic,
antioxidant, antibacterial, antiviral, antifungal, immune boosting and significant
anti-inflammatory properties. The present study aims to explore the efficacy of 1% ALN and AV
gel as a local drug delivery as an adjunct to scaling and root planing (SRP) for the
treatment of degree II furcation defects
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Government Dental College and Research Institute, Bangalore