Local Infiltration Analgesia During Total Knee Arthroplasty

• Status: Unknown status
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective is to evaluate whether local infiltration analgesia (LIA) will reduce oxycodone consumption during the first 48 postoperative hours in patients undergoing total knee arthroplasty (TKA).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Coxa, Hospital for Joint Replacement
• Treatments: Bupivacaine; Epinephrine; Epinephryl borate; Ketorolac; Ketorolac Tromethamine; Levobupivacaine; Racepinephrine

Criteria

Inclusion Criteria:

• Patients requiring primary TKA for primary OA

• Patients aged 75 years or less

• Patients suitable for all applicable devices

Exclusion Criteria:

• Rheumatoid arthritis or other inflammatory diseases

• Patients requiring bone grafting during surgery

• Unwilling to provide informed consent

• BMI > 35

• ASA > 3

• Renal dysfunction

• Allergic to ASA

• Previous high tibial osteotomy or previous osteosynthesis

• > 15 degrees varus / valgus malalignment

• Physical, emotional or neurological conditions which would comprise the patient´s compliance with postoperative rehabilitation and follow-up (e.g. drug or alcohol abuse, serious mental illness, general neurological conditions such as Parkinson, MS, etc.)

• Known sensitivity to materials in the devices