Local Infiltration Analgesia Following Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2008-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect morphine consumption. Secondary end-points are hospital stay, pain intensity and side effects. In an attempt to assess the safety of this technique, knee function and patient satisfaction scores are assessed up to 3 months after surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Region Örebro County
• Treatments: Epinephrine; Epinephryl borate; Ketorolac; Ketorolac Tromethamine; Racepinephrine; Ropivacaine

Criteria

Inclusion Criteria:

• Patients scheduled for total knee arthroplasty

• Aged 20-85 yrs

• ASA physical status I-III and mobility indicating normal postoperative mobilization

Exclusion Criteria:

• Known allergy or intolerance to one of the study drugs

• Serious liver-, heart- or renal decease

• Rheumatoid arthritis

• Chronic pain or bleeding disorder