Local Infiltration Analgesia in Total Knee Arthroplasty
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
40 patients ASA I-III, undergoing total knee arthroplasty were randomly assigned, into one of
two groups, namely group LIA (n=20), where local infiltration analgesia would be administered
intraoperatively; and group sham LIA (n=20), where sham injections of normal saline would be
administered. All patients received a standardized multimodal approach, including pregabalin,
adductor canal peripheral nervous blockade, spinal anaesthesia, paracetamol, and PCA with
morphine. Morphine consumption during the first 24 hours postoperatively was measured and
additionally the investigators recorded: Time of morphine first dose administration, NRS
scores in static and dynamic conditions in 6 hours, 12 hours, 18 hours and 24 hours
postoperatively, complications, patient satisfaction and duration of hospitalization.