Local Injection of Periodontal Pocket Method for the Treatment of Gingivitis

• Status: Recruiting
• Trial end date: 2023-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Preliminary clinical studies have confirmed that injection of freshly prepared HA35 can reduce symptoms and signs of gingivitis or periodontitis. This clinical study is a prospective repeated experiments. The purpose of this study was to verify the effectiveness of HA35 injection therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dove Medical Press Ltd
• Collaborator: Hainan Medical College
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

• Healthy condition and with a clinical diagnosis of mild to moderate gingivitis.

• Male or female volunteers aged 18-60 years.

• Gingival Index (GI) from 1 to 2 (0= Normal gingiva; 1= Mild inflammation - slight change in color and slight edema but no bleeding on probing; 2= Moderate inflammation
• redness, edema and glazing, bleeding on probing)

Exclusion Criteria:

• Healthy condition and with a clinical diagnosis of severe gingivitis.

• Pregnant or lactating females.

• Be concomitantly participating in another clinical study.

• History of any allergic reaction to HA.

• To treat the gingivitis with any other medication/mouthwashes in the period of the study.