Locally Delivered Antibiotics for the Treatment of Periodontitis
Status:
Unknown status
Trial end date:
2020-09-01
Target enrollment:
Participant gender:
Summary
The sample consists of patients with moderate to severe periodontitis who will be subjected
to machanical therapy in combination to local antibiotics. The participants will be divided
into two groups, mechanical therapy with metronidazole hyclate, and mechanical therapy with
minocycline hydrochloride. Both antibiotics will be delivered locally as gels. Outcome
measures include probing pocket depth and several gingival indices. IL6 will be also measured
for all participants.