Overview Lofexidine for Adults Undergoing Lumbar Spine Surgery Status: Completed Trial end date: 2021-04-15 Target enrollment: Participant gender: Summary The primary objective is to investigate the effects of lofexidine in adults undergoing opioid tapering prior to elective lumbar spine surgery. Phase: Phase 4 Details Lead Sponsor: Mayo ClinicCollaborator: US WorldMeds LLCTreatments: Analgesics, OpioidClonidineLofexidine