Overview

Long Term Effects of DPP-IV Inhibitor Treatment in Patients With Type 2 Diabetes

Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
We wish to evaluate the effect of long term treatment with a DPP-IV inhibitor on the function of the incretin hormones Hypothesis We hypothesize that that a gradual improvement in metabolic control induced by DPP-IV inhibitor (Januvia®) treatment significantly ameliorates the impaired secretion and potency of GLP-1 and leads to a restoration of the lost action of GIP.
Phase:
Phase 3
Details
Lead Sponsor:
University Hospital, Gentofte, Copenhagen
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Gastric Inhibitory Polypeptide
Incretins
Sitagliptin Phosphate