Long-Term Lithium Treatment for Aggressive Conduct Disorder

• Status: Completed
• Trial end date: 2005-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine the long-term effects of lithium used to treat children and adolescents with aggressive conduct disorder (severe aggression).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Drexel University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Lithium Carbonate

Criteria

Inclusion Criteria:

1. Males and females

2. Ages between 9 and 17 years.

3. Conduct disorder according to DSM-IV (As rated on the DICA-IV).

4. The aggression criterion at screening

Exclusion Criteria:

1. Mental Retardation.

2. Pervasive Developmental Disorder(s).

3. Major Depressive Disorder or Dysthymic Disorder.

4. Bipolar Disorder.

5. Psychotic Disorder (including Schizophreniform Disorder and Schizophrenia).

6. Major medical problem such as cardiac, renal, and thyroid diseases, or seizure disorder.

7. History of psychoactive medication in the previous 2 weeks.

8. Current Pregnancy in females.

9. History of Substance Dependence in the past month.

10. Prior to the proposed study, a history of lithium treatment with serum lithium levels of 0.4 mEq/L or higher for a cumulative period of greater than 10 days.