Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to determine whether clonazepam and paroxetine are effective in the treatment of panic disorder. Efficacy was evaluated in short-term, long-term and post-treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidade Federal do Rio de Janeiro
• Collaborator: Conselho Nacional de Desenvolvimento Científico e Tecnológico
• Treatments: Clonazepam; Paroxetine

Criteria

Inclusion Criteria:

• Diagnosis of panic disorder, with or without agoraphobia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, text revision (DSM-IV-TR) criteria, as determined by a structured clinical interview.

• At least two panic attacks in the week preceding their inclusion in the study.

Exclusion Criteria:

• Patients unable or unwilling to provide written informed consent.

• Did not complete all the evaluations before study initiation.

• Had comorbidities that could affect clinical evaluation including drug abuse, neurological disorders, or severe personality disorder.