Long-term Effect of θ Burst Magnetic Stimulation on Clinical Symptoms of Alzheimer Disease
Status:
Recruiting
Trial end date:
2022-04-30
Target enrollment:
Participant gender:
Summary
This was a randomized, single-blind, parallel, placebo-controlled clinical trial assessing
the efficacy of neuronavigational TBS among patients with AD. Fourty late-onset AD were
included in the study, all the patients were divided into TBS groups and drug treatment
group. Drug intervention group AD patients with drug regimen (donepezil 5mg / d) and primary
care guidance, once every three months follow-up. TBS group is treated with TBS (a course of
treatment every 3 months); after completing 4 treatments/follow-ups a year, evaluate the
changes in MoCA, other clinical symptoms and multi-domain cognition tests, and brain Changes
in structure and function.