Overview

Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies

Status:
Completed

Trial end date:
2019-06-30

Target enrollment:
0

Participant gender:
All

Summary

The objective of this retrospective observational study is to compare commonly prescribed bipolar disorder medications for their impact on: (1) hospitalization; (2) suicide attempts and self-harm; and (3) risk of drug-induced adverse effects such as kidney disease and diabetes mellitus. In addition, the investigators will examine heterogeneity of treatment effect by co-morbidity within pediatric, adult, and elderly sub-populations. Patient focus groups are convened to elicit additional questions and provide feedback on results.

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of New Mexico

Collaborators:

CGStat LLC
Montana State University
National Alliance on Mental Illness
National Alliance on Mental Illness Montana
National Alliance on Mental Illness New Mexico
National Alliance on Mental Illness Westside Los Angeles
Patient-Centered Outcomes Research Institute
Risk Benefit Statistics LLC

Treatments:

Aripiprazole
Asenapine
Bupropion
Carbamazepine
Citalopram
Clozapine
Desvenlafaxine Succinate
Doxepin
Duloxetine Hydrochloride
Fluoxetine
Fluvoxamine
Haloperidol
Lamotrigine
Lithium Carbonate
Lurasidone Hydrochloride
Mirtazapine
Olanzapine
Oxcarbazepine
Paliperidone Palmitate
Paroxetine
Perphenazine
Quetiapine Fumarate
Risperidone
Sertraline
Valproic Acid
Venlafaxine Hydrochloride
Vilazodone Hydrochloride
Ziprasidone

Criteria

Inclusion Criteria:

- Two or more instances of bipolar disorder diagnoses within administrative claims
records

Exclusion Criteria:

- Patients with less than 1 year of history in the database