Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease
Status:
Recruiting
Trial end date:
2025-05-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine how inflammation is related to other changes in the
brain that occur during the progression of Alzheimer's disease. The investigators are also
studying how inflammation is related to the symptoms that first occur in patients with
Alzheimer's disease (AD). For this reason, the investigators are asking people with different
versions of Alzheimer's disease to participate. This includes patients with either:
- Posterior cortical atrophy - a version of Alzheimer's disease with vision difficulties
- Logopenic variant primary progressive aphasia - a version of Alzheimer's disease with
language difficulties
- Amnestic Alzheimer's disease - a "typical" version of Alzheimer's disease with memory
difficulties
- The investigators are also enrolling older adults with normal visual, language, and
memory function.