Lornoxicam Versus Etoricoxib in Postoperative Pain After Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess efficacy and safety of lornoxicam compared with that of etoricoxib after total knee replacement.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Foisor Orthopedics Clinical Hospital
• Treatments: Etoricoxib; Lornoxicam; Piroxicam

Criteria

Inclusion Criteria:

• ASA I-III

• weight (kilos) over 40 kg

• height (centimeters) over 155 cm

• non-anemic

• indication for primary TKA

Exclusion Criteria:

• history of asthma

• peptic ulcer

• severe hepatic or renal dysfunction

• neuropathies

• bleeding disorders

• uncooperative

• drugs abuse

• sensibility to the drugs used

• long acting nonsteroidal antiinflammatory drugs (NSAID) in the last 4 days preoperative

• cerebrovascular and peripheric vascular disease

• arterial hypertension (HTA) not adequately controlled

• congestive heart failure