Lornoxicam vs. Paracetamol After Lower Abdominal Surgery
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Background: The aim of this prospective, randomized, double-blind study is to determine the
most effective supplemental analgesic, paracetamol or lornoxicam for postoperative pain
relief after lower abdominal surgery.
Methods: Sixty patients scheduled for lower abdominal surgery under general anesthesia were
randomly allocated to receive either isotonic saline (Control group), intravenous paracetamol
1 g every 6 h (Paracetamol group) or lornoxicam 16 mg then 8 mg after 12 h (Lornoxicam
group). Additionally pain was treated postoperatively using morphine patient-controlled
analgesia. Postoperative pain scores measured by the verbal pain score (VPS), morphine
consumption and the incidence of side effects were measured at 1, 2, 4, 8, 12 and 24 hours
postoperatively.