Overview Losartan to Reverse Sickle Nephropathy Status: Completed Trial end date: 2015-12-01 Target enrollment: Participant gender: Summary Sickle cell disease causes kidney damage with increasing age, leading to chronic kidney disease and renal failure in nearly one third of patients with sickle cell disease. Currently, there is no treatment for sickle cell related kidney disease. Phase: Phase 2 Details Lead Sponsor: Children's Hospital Medical Center, CincinnatiTreatments: Losartan