Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS)
Status:
Not yet recruiting
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
Vasoplegia is an important determinant for adverse postoperative outcome and is observerd in
5% to 54% of patients undergoing cardiac surgery using cardiopulmonary bypass (CPB).
Postoperative vasoplegia is defined as a state with low systemic vascular resistance despite
a normal or high cardiac output, and the need for vasopressor therapy.
Steroids attenuate the inflammatory response to cardiopulmonary bypass,but their effect on
clinical outcomes is uncertain.
This is a double-blinded, randomized, clinical trial designed to determine the efficacy of
low dose corticosteroid infusion in vasopressor free-days in vasoplegia after cardiac
surgery.