Low Dose Cyclosporin A in Primary Sjögren Syndrome

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Sandimmun optoral (Cyclosporin A) is used for the musculoskeletal manifestations of Primary Sjögren Syndrome

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Charite University, Berlin, Germany
• Treatments: Cyclosporine; Cyclosporins

Criteria

Inclusion Criteria:

• Diagnosis of a primary Sjögren´s Syndrome

• Liver values above 1,5 ULN

• uncontrolled arterial hypertension

• intraarticular or systemic use of Glucocorticoids in the last 4 weeks before

• begin with Study medication

Exclusion Criteria:

• pre-treatment with Cyclosporine A

• Infection

• Neoplasia

• relevant cardiac, pulmonary, neurologic or psychiatric disease

• life-Vaccination within 4 weeks before begin with study medication

• pregnant or breast-feeding

• weight under 45kg or more than 110kg