Overview

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

Status:
Not yet recruiting
Trial end date:
2026-05-01
Target enrollment:
0
Participant gender:
All
Summary
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients undergoing posterior spinal fusion for idiopathic scoliosis.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Children's Mercy Hospital Kansas City
Treatments:
Dexmedetomidine
Criteria
Inclusion Criteria:

- Diagnosis of idiopathic scoliosis

- Undergoing a posterior spinal fusion of at least 5 levels with both thoracic and
lumbar involvement

Exclusion Criteria:

- Known allergy to dexmedetomidine or any of the standard medications used intra or post
operatively

- Patients with a history of chronic pain currently taking opioids, TCA's,
Gabapentinoids

- Medical contraindications to administration of dexmedetomidine, unstable cardiac
status, (prolonged Qtc, life threatening arrhythmias, use of digoxin)

- Moya Moya disease