Low Dose Hyperbaric Bupivacaine and Dexmedetomidine as an Adjuvant, Caesarean Section

• Status: Completed
• Trial end date: 2019-01-10
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to evaluate the effectiveness of low dose scheme with dexmedetomidine as an adjuvant. Taking in consideration optimum intraoperative surgical conditions, best post-operative pain free experience, and more stable hemodynamic.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Menoufia University
• Treatments: Bupivacaine; Dexmedetomidine

Criteria

Inclusion Criteria:

• Full-term pregnant women

• Singleton gestation

• American Society of Anaesthesiologists (ASA) physical status classes II and I

Exclusion Criteria:

• Preterm pregnancy (<37 wks. gestation)

• Multiple gestation

• Cardiovascular disease (e.g., preeclampsia, hypertension) and the use of antihypertensive medications

• Asthma and allergy to non-steroidal anti-inflammatory drugs

• Conditions that prevent spinal anaesthesia

• Failed spinal block and conversion to general anaesthesia

• A history of established chronic pain

• Drug addiction

• A psychiatric disorder

• Inability to communicate effectively