Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
The primary objectives of the study are to evaluate the efficacy of subdissociative dose
intravenous ketamine compared with intravenous morphine in relieving acute pain in the ED.
Secondary objectives will include the rate of adverse effects and need for rescue analgesia.
The hypothesis is that intravenous administration of subdissociative dose ketamine at 0.3
mg/kg is superior to intravenous morphine at 0.1mg/kg in treating moderate and severe acute
pain in patients presenting to the ED.