Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia
Status:
Completed
Trial end date:
2020-02-25
Target enrollment:
Participant gender:
Summary
patients who had >3 on Murray score and >6 on CPIS allocated randomly in two groups 120
patients in each. Group A received 30 mg/kg methyl-prednisolone slowly intravenous in 250 mL
normal saline every 8 hours for only 48 hours while group B received 1 mg/kg/day
methyl-prednisolone divided to three doses given every 8 hours for two weeks. Duration of the
study last 16 days, Morbidity considered if no improvement in any or all clinical parameters
of both Murray and CPIS scores and failure of weaning of patients from the ventilator at the
studied period.