Overview

Low-dose ITI Strategy for Children in Hemophilia A With High-titer Inhibitor and Poor ITI Risk in China

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The study start on January 18, 2017. The Severe(FⅧ<1%) and moderate hemophilia A (FⅧ1%~5%)children with high titer inhibitor(historical peak inhibitor titer≥5BU ) combining with poor ITI risk(s) were enrolled. The low-dose ITI was alone or combined with immunosuppression.
Phase:
Phase 4
Details
Lead Sponsor:
Beijing Children's Hospital
Treatments:
Factor VIII
Prednisone
Rituximab