Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Status:
Completed
Trial end date:
2018-06-25
Target enrollment:
Participant gender:
Summary
Postpartum depression is common in mothers early after childbirth and produces harmful
effects not only on mothers, but also on infants and young children. Parturients with
prenatal depression are at increased of postpartum depression. Low-dose ketamine can be used
for antidepressant therapy. We hypothesize that low-dose ketamine has a therapeutic effect on
parturients with prenatal depression. This study is designed to investigate whether low-dose
ketamine administered during cesarean delivery can decrease the incidence of postpartum
depression in parturients with prenatal depression.