Low vs. Very Low Dose of Prophylactic Tranexamic Acid for Bleeding Reduction During Rhinoplasty

• Status: Unknown status
• Trial end date: 2019-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether very low dose of preoperative tranexamic acid (5mg/kg) is as effective as low dose (10mg/kg) for intraoperational bleeding reduction in patients undergoing elective rhinoplasty surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bartłomiej Wódarski
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• age > 18 y.o.

• American Society of Anesthesiologists Physical Status Classification (ASA) 1-2

• signed informed consent form after reading the information about the study and talking with one of the investigators

Exclusion Criteria:

• pregnancy

• known allergies for tranexamic acid or any other substance in Exacyl

• deep vein thrombosis

• Hormone Replacement Therapy or oral contraceptive usage

• anticoagulants usage

• obesity - BMI (body mass index) >30 kg/m2

• renal disease, as glomerular filtration rate (GFR) <60 ml/min/1,73 m*m

• seizures or epilepsy in the past