Lowering Serum Uric Acid to Prevent Acute Kidney Injury
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Acute kidney injury is associated with a rise in serum uric acid during cardiovascular
surgery and can cause poor blood flow to the kidneys making them vulnerable to kidney injury.
We hypothesize that hyperuricemia, particularly if chronic and marked, is a risk factor for
acute kidney injury. The preoperative lowering of serum uric acid will reduce the incidence
of acute kidney injury following cardiovascular surgery.