Overview

Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation

Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
Patients requiring opioids for post-operative pain control following elective orthopedic procedures which has resulted in constipation symptoms, and who are in inpatient rehabilitation will be randomized to two different treatment arms: lubiprostone or senna. Baseline scores regarding constipation and a quality of life bowel questionnaire will be compared the day following 6 days of treatment intervention.
Phase:
N/A
Details
Lead Sponsor:
Rehabilitation Institute of Chicago
Shirley Ryan AbilityLab
Collaborator:
Takeda Pharmaceuticals North America, Inc.
Treatments:
Analgesics, Opioid
Lubiprostone
Senna Extract
Sennoside A&B